Thyroid eye disease (TED) is a condition where the immune system causes growth of the muscle and tissue around the eyes. Typically, the active or inflammatory stage of TED lasts one to three years and symptoms can range from mild to severe. Symptoms of TED may include bulging eyes, redness, irritation, swelling, and double or blurry vision. TED can affect your life in many adverse ways, from things as simple as watching TV or reading, to affecting your ability to work and to drive. If left untreated, TED may potentially lead to severe vision problems or even vision loss.
Adding to this discomfort and irritation, TED can also change your physical appearance to the point that it affects your mental health, with feelings of depression, increased isolation, and a loss of self-worth.
Researchers continue to explore TED treatments and are working to test a possible oral medication option through clinical studies like LIDS, which is testing an investigational (or study) drug called linsitinib to see how it works in adults with active, moderate-to-severe TED. Study volunteers can help us in this important research. Thank you for considering participation in this study.